River East lies in the northeast quadrant of Winnipeg, running along the east shore of the Red River. It is bounded to the north by Glenway Ave, and to the south by a set of railroad tracks near Mission St. The main east-west thoroughfares are Chief Peguis Trail (Route 17), and Nairn Ave (Route 37). The main north-south thoroughfares are Henderson Hwy (Route 42), Gateway Rd, and Lagimodière Blvd (Route 20).